A case of intranasal extramedullary plasmacytoma

Abstract

We herein report a case of extramedullary plasmacytoma (EMP) in the nasal cavity. A 75-year-old man was referred to our department because of recurrent left nasal hemorrhaging when blowing his nose and a tumor in the left nasal cavity. He had been aware of left nasal obstruction for four months. Nasal fiberoscopy showed a 15-mm hemorrhagic mass in the left nasal cavity, and enhanced computed tomography revealed a well-enhanced mass at the corresponding site. The patient underwent nasal endoscopic tumor resection under general anesthesia. The histopathological examination findings were suspicious for EMP. Serum electrophoresis was positive for IgG-κ type M protein, urine Bence-Jones protein was negative, bone marrow puncture was normal, and no other organ damage was observed. Based on the above findings, he was diagnosed with primary EMP of the nasal cavity. There has been no evidence of recurrence at more than one year after surgery. Although the 5-year survival rate of EMP in the head and neck region has been reported to be approximately 70%, long-term follow-up for this patient will be necessary because of the poor prognosis in cases with local relapse or transformation to multiple myeloma.