jibi to rinsho
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
Clinical Application of Lisozym to Chronic Sinusitis
Pathohistological Examination of Mucosa of Maxillary Sinus
Ichiro TaniKozo UchidaTakeshi TakeshitaTeruo TanemuraShin Miyata
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1965 Volume 11 Issue 3 Pages 181-188

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Abstract
The authors applied “Lisozym”( a sort of Mucopolysaccharase generally existing in living bodies) to 35 patients suffering from chronic sinusitis, and examined its effects pathohistologically. 90 mg of this drug a day was administered internally, from immediately after the operation of one side till the next operation of the other side (7-23 days). About the obtained 70 mucosas, the efficiency of the drug was estimated by means of the extend of oedema, dilatation of capillary vessels, cell infiltration, exforation of epitheliums or by means of the condition of cilia.
The efficiency rate was 54.2% and no after-effect was observed. And the efficiency was higher in the patients below twenty years, and became remarkable after 2 weeks administration of it.
“ Lisozym” is supposed to be efficient in little children to whom operation is difficult to be applied, and is recommended to be tried for 3 weeks at least.
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