jibi to rinsho
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
Audiological Examinations and the Effects of Some Drugs on the Deafness Caused by Factory Noise of 115-135 phons for Eight Months
II The Effects of Some Drugs
Toshihiko YokoyamaHiroo Minoyama
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1968 Volume 14 Issue 2 Pages 124-135

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Abstract

Vitamedin (compound of Vitamin Bi, B6 and B12), Verina CI\Tylidrin hydro- chloride) and Adetphos (Adenosine triphosphate) were administrated to 13 workers for 2 months. They had complained of dim hearing caused under the noisy circumstances of about 115-135 phons for about 8 months.
All cases showed remarkable recovery of hearing 1 month after the administ- ration of the drugs. The statistical examination proved that the results were reliable. Especially, hearing was much recovered in those who had had hearing-loss of above 60 dB in speech frequency area. In addition to the above drugs, they were administrated Biotinin (active Vitamin B1) intravenously and Decadron Nexamethazone) internally. And also they were arranged to work in the other less noisy branch of the factory.
Their audiograms showed that their hearing had the tendency of getting low when the administration of Biotinin and Decadron was ceased a month after the commencement of medical treatment.
It is suggested that these improvement of hearing was due to the versatility of the noise-induced disturbance of the inner ear in its early stages and that the administration of the drugs hastened the recovery.

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