Abstract
51 year-old male was treated in our hospital complaining of hoarseness and dyspnea, after three years when his 56 year-old elder brother had treated.
They had similar smoking histories (1200 of Brinkman index), same occupation of fisherman and showed same pathological findings of squamous cell carcinoma (T3N0, T4N0). They were treated similarly emergency tracheotomy followed by total laryngectomy with good course.
Their family history revealed other two cancers, gastric cancer of the father and cancer of the breast of the sister. Not only extrinsic factors but genetic factor as intrinsic one in this case were suggested.
