Clinical Evaluation of Lenampicillin (KBT-1585) in the Treatment for Sinusitis

Abstract

Clinical effectiveness and safety of KBT-1585 in the treatment for sinusitis was studied. 1. Thirty-two patients entered into the trial and they consisted of 10 cases with acute sinusitis, 9 with acute exacerbation of chronic sinusitis and 13 with chronic sinusitis. 2. The efficacy rate judged by the doctor in charge was 67.7% (21/31), by the standard criteria was 65.6% (21/32). 3. The bacteriological responses of patient were favorable in 90% (18/20). 4. As the side effect, itching was observed in 1 case out of 32 cases (3.1%). No abnormal laboratory findings were observed. From the above results, KBT-1585 was considered to be a useful drug in the treatment for sinusitis.