A Case Report of Phenytoin Intoxication

Abstract

We reported a case of phenytoin intoxication with a review of literatures. The patient with convulsion due to normal pressure hydrocephalus had been treated with 500 mg of phenytoin orally daily for 3 years. On the first visit, he complained of severe dysequilibrium. Neuro-otological examination revealed that the brain stem was responsible for the disturbance. Most of the abnormal neuro-otological findings were diminished, as the serum phenytoin level went down. It was concluded that the neuro-otological abnormalities were induced by a high serum level of phenytoin.