jibi to rinsho
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
Volume 31, Issue 5
Displaying 1-18 of 18 articles from this issue
  • Some Considerations on the Hearing-Phonation System in Man
    Kensaku MIYAMOTO
    1985 Volume 31 Issue 5 Pages 887-916
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Some interesting similarity exists between developmental systems such as those found in avian and in human vocalization. And there are some analogies between the organization of the neural systems which control the avian songs and human speech. Furthermore, the Mynah will imitate human speech (vowel, and consonants) and variety of sounds in its immediate environment when it is kept in captivity since young. Therefore, among birds the Mynah seems to be an excellent subject for experimental studies on the auditory and vocal system in human. The process of imitative learning in birds parallels the early stage of acquisition of human speech in many points. When the Mynah is breeded separately and given affluent auditory stimulus, the vocal mimicry is accelerated and its contents show much variety. This fact supports the importance of the mother's talking to the infant for the establishment of its babbling and also for the speech development. It seems that the Mynah must hear its own vocal reproductions to match its vocal motor output to its memory template. It is probable that in the Mynah, auditory feedback is necessory to develop the exact and clear vocal mimicry. In the Mynah the frequency-intensity characteristic of hearing, i. e., the audiometric curve (0.1-15.0KHz, the most sensitive frequency band: 2.0-4.0KHz), could be constructed from the conditioned response to the sound stimulus. A comparison of the avian vocalization and the audiovocalization system in man was discussed.
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  • Hiroyuki YOSHIMURA, Shoichi MAEDA, Tatsuya FUJIYOSHI, Yuichi KURONO, H ...
    1985 Volume 31 Issue 5 Pages 917-920
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    We have performed middle ear surgery on 82 ears with chronic otitis media during the past 3 years and 8 months. A labyrinthine fistula was found in 8 ears which had cholesteatoma otitis. A fistula was present at the lateral semicircular canal in 7 cases, and in one case there were two fistulas at the lateral semicircular canal and the basal turn of the cochlea. A case having two fistulas is very rare.
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  • An attempt at its definition in clinical terms
    Kohichi YASUDA
    1985 Volume 31 Issue 5 Pages 921-930
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Nowadays the diagnosis of MÉNIÈRE's disease usually is made on the basis of the presence of such subjective symptoms as vertigo, tinnitus and hearing impairment. However, experience in routine practice clearly indicates how unreliable and uncertain patients are in their awareness of the symptoms they have. A total of 10 cases presented by MÉNIÈRE in his treatises published in 1861 were invariably of an idiopathic inner ear disorder, presently designated as MÉNIÈRE's disease or sudden deafness. MÉNIERÈ's true intention in publishing his famous four articles was to contend that there exists an idiopathic disease characterized by attacks of symptoms of inner ear origin. MÉNIÈRE himself never discriminated the presently well-established triad (i. e. vertigo, tinnitus and hearing impairment) from other accompanying manifestation, such as vomiting, facial pallor and syncope. Therefore, there would be no necessity of considering vertigo, tinnitus and hearing loss as essential to the diagnosis of MÉNIÈRE's disease, nor any reason to rely solely on the patient's subjective symptomatology in making a diagnosis of the disease. Recent progress in otoneurology has provided us otologists with far more reliable objective means of demonstrating inner ear disorder (such as tests for equilibrium function and audiometry) than patients' subjective complaints. Based on the MÉNIÈRE's articles and my personal experiences, I tentatively defined MÉNIÈRE's disease as an inner ear disorder of nonextrinsic origin characterized by more or less clearly definable, alternating periods of attack and attack-free intermission. I reviewed 50 of my cases in an endeavor to examine the legitimacy of this definition.
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  • Conservative Treatment by Estrogen and Progesterone
    Satoshi KITAHARA, Tetsuzo INOUE, Yukio TODA, Jun IIDA, Kumi NAKAJIMA, ...
    1985 Volume 31 Issue 5 Pages 931-938
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Androgenic dysphonia is considered to be due to an organic change in the vocal cords caused by the metabolic effect of androgenic hormones or anabolic hormones. At present a surgical treatment for this disease, in which the pitch is increased by the predominance of the action of the crico-thyroid muscle, is available, but we can not find any report on a conservative treatment for this disease. There are reports that progesterone exhibits catabolic activity in man. In this study, the presence or absense of improvement of dysphonia by administration of a female sex hormone was determined experimentally. An androgenic hormone was injected to female chickens to induce dysphonia (hoatseness), followed by a single injection of estrogen or progesterone, or the simultaneous injection of both to observe changes in the dysphonia. With a single administration of estrogen or progesterone, dysphonia improved only in the progesterone-treated group. In the group in which the combination of estrogen and progesterone was given to the same individual, dysphonia improved and the voice was restored to almost normal. These results revealed that androgenic dysphonia was improved by administration of a female sex hormone to the female chicken.
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  • Hidemichi ASHIKAWA, Mamoru MORITA
    1985 Volume 31 Issue 5 Pages 939-944
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    A 15-year-old male was referred to our clinic for repeated attacks of swelling in the left cheek over the previous decade. Each time the swelling occurrred, paracentesis was performed with the removal of bloody fluid. Physical examination showed two different masses; the lower mass was firm and nodular, the upper was elastic and fluctuant. There was no tumor staining in the cervical angiogram, or contrastive enhancement in X-ray CT. Two well-demarcated cysts filled with coagula (the lower mass) and yellow serous fluid (the upper mass) were identified intraoperatively and were successfully removed. Histological examination showed that both tumors were venous hemangioma, and this case was classified as Spannaus 4 and Murakami's 3 type blood cyst. The postoperative course was uneventful, and there was no sign of recurrence two years after the operation.
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  • Kazuo KUMOI, Tetsu TABUCHI, Kiyomi TANIGUCHI
    1985 Volume 31 Issue 5 Pages 945-948
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    We reported a case of phenytoin intoxication with a review of literatures. The patient with convulsion due to normal pressure hydrocephalus had been treated with 500 mg of phenytoin orally daily for 3 years. On the first visit, he complained of severe dysequilibrium. Neuro-otological examination revealed that the brain stem was responsible for the disturbance. Most of the abnormal neuro-otological findings were diminished, as the serum phenytoin level went down. It was concluded that the neuro-otological abnormalities were induced by a high serum level of phenytoin.
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  • Jin KANZAKI, Hidenobu TAIJI, Eiichirou ITAMI, Hajime AMANO, Chiyonori ...
    1985 Volume 31 Issue 5 Pages 949-954
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Tinnitus frequencies and test tone waves corresponding to the tinnitus were examined with a newly-devised tinnitus synthesizer in patients with monaural tinnitus. Reanalysis of the tinnitus by the above synthesizer revealed square waves, delta waves or clipped sine waves among those which onomatopoeias were identified as pure tones or band noises by a conventional audiometer. The percentage of patients whose tinnitus matched with sine waves was 48%, synthesized clipped sine waves or delta waves or square waves-30%, noise-12%, and unclassifiable-9.6%. No definite relationship was found between the audiometric configuration and the results of the tinnitus measurement. No specific relationship was found between the wave form of the tinnitus and the diagnosed disease such as sudden deafness, Ménière's disease and acoustic neuroma. The tinnitus identified as band noise using an audiometer was matched with delta or square waves or an FM tone with the tinnitus synthesizer. Long term studies are necessary to confirm the repeat-ability of the above findings with this synthesizer, and to learn what kinds of test tones are needed for better tinnitus measurement.
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  • Analysis from initial symptoms to established diagnosis
    Kunihiko TSUTSUMIUCHI, Yuzuru TANIKAWA, Hisao MIYASHITA, Tomohiko NIGA ...
    1985 Volume 31 Issue 5 Pages 955-958
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    In 21 patients with primary nasopharyngeal cancer encountered at Tokyo Metropolitan Komagome Hospital in the years 1976 through 1984, initial symptoms, presenting symptoms and duration between the onset of symptoms and the initial clinical visit were reviewed. Three short case histories were also presented. The most frequent initial symptom was nasal followed by otic, cranial nerve, a mass in neck and a sore throat. The most frequent presenting symptom was nasal followed by a mass in neck, cranial nerve and otic. The period from the initial symptom to the first visit to our hospital was 12.5 months on an average. For early diagnosis, the authors stressed it was important for otolaryngologist, physician, surgeon and neurosurgeon to suspect nasopharyngeal cancer, when the symptoms described above were presented.
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  • Keiichi ICHIMURA, Yasuhiro SERIZAWA, Hiroshi MIYASHITA, Yoshihiro WADA ...
    1985 Volume 31 Issue 5 Pages 959-966
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Branchio-oto-renal syndrome (BORS) was defined by MELNICK et al as the clinical entity that has branchial anomalies, hearing impairment and renal dysplasia. We presented a 10-year-old girl who fit well with the diagnostic criteria of BORS (bilateral preauricular pits, bilateral lateral cervical fistulae, mixed type of bilateral hearing loss, and left renal hypoplasia). The mixed type of hearing loss turned out to be due to ossicular deformity and cochlear hypoplasia based on target imaging CT and surgery. We also showed a 54-year-old lady with branchio-oto syndrome (BOS). Her family history revealed that 7 out of 10 siblings appeared to have BOS, and her father and one of her elder sisters appeared to have BORS. This supports the concept that BOS and BORS is a single disease entity.
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  • Noritake WATANABE, Akiteru YUMISAKI
    1985 Volume 31 Issue 5 Pages 967-971
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    The sphenoid sinus mucocele is rare. We presented a case of a huge sphenoid sinus mucocele extending to the left pterygopalatine fossa in 72-year-old woman. No case of such a huge sphenoid sinus mucocele has been reported previously. The recognition and expansion of the sphenoid sinus mucocele was investigated by means of conventional and computed tomographies.
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  • Katsuichiro OHSAKI, Mamoru KIMURA, Ikuo INOKUCHI, Tomoaki SUGIURA, Kei ...
    1985 Volume 31 Issue 5 Pages 972-981
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    For the purpose of measuring approximate frequency values accurately against subjective tinnitus, the pitch match test was attempted with thirty tinnitus ton es in twenty-eight ears (twenty-two cases). A characteristic of this test is to use the pure tone frequencies at each tone of the heptatonic scale on the basis of a temperament musical scale as the test tone. Ten kinds of onomatopoetic sounds in tinnitus of various otologic diseases were tested. The results were as follows: Approximate frequency value was measured in nineteen out of twenty-two cases (86.4%). The lowest approximate frequency value was 98.00Hz=C (sol) and the highest approximate frequency was 4186.08Hz=c5 (do) in these cases. Approximate frequency value in three cases (13.6%) were not measurable. In this paper, we discussed the relation between ΔF1/F1×100 (F1: each tone frequency on heptachord. ΔF1: difference in frequency between F1 and neighboring frequency of each tone being higher in pitch than F1) and relative frequency difference limen, and the difference between the heptatonic scale and temperament scale.
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  • with Special Emphasis on the Course of Tinnitus
    Tsuneyuki OKU, Isamu WATANABE, Makoto HASEGAWA, Hideo EDAMATSU
    1985 Volume 31 Issue 5 Pages 982-987
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Tack operations (Com 1967) were performed in three cases of unilateral Meniere's syndrome. Follow-up observations were made two to four years after the operation. Dizziness disappeared and tinnitus improved markedly in all cases, however, in two cases, slight dizziness or tinnitus appeared again repeatedly for a very short time and then completely disappeared. These findings might suggest that the bulging endolymphatic wall had been broken repeatedly by the tip of the Tack. Hearing deteriorated after the operation in two cases; however, it recovered gradually to the level of the pre-operative examination.
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  • Mamoru TSUKUDA, Shuji SAWAKI
    1985 Volume 31 Issue 5 Pages 988-992
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    The clinical effects of coenzyme Q10 (CoQ10) against the side effects induced by anti-cancer drugs were investigated in 409 patients who have head and neck cancer, from April in 1977 to March in 1983. The investigated side effects were abnormalities of ECG and pulmonary function insufficiency which were mortal to patient's life. Coenzyme Q10 (CoQ10), isolated from the electron transfer system in the mitochondria, has been reported to produce favorable protective and restorative effects on myocardium caused by ischemia or by cardiotoxic drugs such as adriamycin (ADM) in both clinical and experimental studies. Result: Using the anthracycline anti-cancer drugs, adriamycin (59 cases), acracinomycin (32 cases), abnomalities of ECG were demonstrated to be in lower incidence than control group which has been reported already on the other hand pulmonary function insufficiency, reversible lung fibrosis which were induced by Peplomycin appe ared in only 1.6% (5cases).
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  • Shunkichi BABA, Harugi KINOSHITA, Yoshito MORI, Kenji SUZUKI, Masaru O ...
    1985 Volume 31 Issue 5 Pages 993-1011
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    The efficacy, safety and utility of S6472 750mg/day (in 2 divided doses) were compared with those of Cefaclor (CCL) 750mg/day (in 3 divided doses) in a double-blind. study in the treatment of 242 patients with acute suppurative otitis media or acute exacerbation of chronic suppurative otitis media. 1. In the evaluation of clinical efficacy by the doctors in charge, the efficacy rate was 58.9% for the S6472 group and 55.4% for the CCL group. In evaluation on the basis of the criteria set by the committee, the efficacy rate was 56.1% for the S6472 group and 59.4% for the CCL group. In neither evaluation, was there a significant difference between the two groups. 2. The bacteriological response (elimination rate) was 71.3% in the S6472 group and 60.2% in the CCL group. There was no significant difference between the two groups. 3. Side effects occurred in 4 (3.4%) of 116 cases in the S6472 group and 1 (0.9%) of 115 cases in the CCL group. Drug related aggravation of the laboratory test were observed in 1 case in the S6472 group and 2 cases in the CCL group. There was no significant difference between the two groups. 4. In utility evaluation, the acceptability rate covering “satisfactory” and “very satisfactory” was 58.9% for the S6472 group and 53.9% for the CCL group. There was no significant difference between the two groups. These results indicate 750 mg/day of S6472 in 2 divided doses has the same effectiveness, safety and utility as 750 mg/day of CCL in 3 divided doses for the treatment of suppurative otitis media.
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  • Michihiko NOZUE
    1985 Volume 31 Issue 5 Pages 1012-1016
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Cinepazide (Brendil) was administrated to 30 patients with vertigo and evaluated its effectiveness. The results were as follows.(1) Subjective symptoms were improved in 90% of Ménière's disease, 66.7% of paroxysmal positional vertigo and 70% of other vertigenous diseases.(2) Rotatory vertigo was improved in 78.2%, swaying dizziness in 46.6%, equilibrium disturbance in 75%. Furthermore, nausea was reduced in 80%, heavy-head and headache in 92.9% and stiff shoulders in 95.7%.(3) Although many patients had no objective findings, the findings which was noted were reduced in 61.5%. In all cases, there were no side effects of this drug. These results suggest that Brendil is useful in the treatment of the patients of vertigo.
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  • Shigeaki SHIRABE
    1985 Volume 31 Issue 5 Pages 1017-1022
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    The effect of Isosorbide (Isobide-solution) as an oral hyperosmotic diuretic agent was evaluated in 25 patients with Ménière's disease. Old and recurrent cases during the past three years were studied. The period of administration was a minimum of two to four weeks and the solution was administered orally 3 times a day (70-90ml). Subjective vertigious symptoms improved in 21 cases (84%), tinnitus improvement in 36% of the cases and hearing improvement in 32% of the cases. In 15 patients with low frequency hearing loss, a 7 dB mean hearing level improvement in low frequency was observed during treatment. In two patients with long term periodic administration of Isosorbide, attacks of vertigo did not occur for the past two years. No aggravation of symptoms or side effects were observed.
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  • A Comparative Double Blind Study with Cefaclor
    Shozo KAWAMURA, Rinya SUGITA, Takatsugu ITABASHI, Hiroshi WATANABE, Yu ...
    1985 Volume 31 Issue 5 Pages 1023-1046
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    For the purpose of comparing the clinical effectiveness, side effect and utility of sultamicillin (SBTPC) and cefaclor (CCL) in purulent otitis media, SBTPC and CCL were administered orally for 7 days at the daily dose of 375mg t. i. d. and 250mg t. i. d., respectively. A double blind method revealed the following; 1) SBTPC and CCL were administered to 127 and 131 patients. In each group, 111 patients were examined for clinical efficacy of the respective treatment, and 126 patients were evaluated for safety in each group. 2) The clinical effectiveness was judged by the criteria of attending doctors and that of the committee. The efficacy rate, judged by doctors, of SBTPC group (67.6%) was superior to that of CCL group (P<0.05). On the other hand, the effectiveness rate, judged by the committee, of SBTPC group and CCL group were 61.3% and 50.5%, respectively. No significant difference was noted in both groups. 3) The bacteriological effectiveness (eradication rate) was 63.9% in SBTPC group and 55.3% in CCL group, and no significant difference was noted. 4) As judged by committee, the overall improvement rate (P<0.01) and improvement rate on the 7th day (P<0.05) of SBTPC group were superior to that of CCL group. 5) Side effects occurred in 9 (7.1%) of 126 cases in the SBTPC group and in 6 (4.8%) of 126 cases in the CCL group. There was no significant difference between the two groups. 6) The rating of very satisfactory and satisfactory of SBTPC were 29.7% and 38.7% respectively and that of CCL group were 25.2% and 32.4%. There was no significant difference between the two groups. These results indicate that SBTPC is a high-ly useful drug for the treatment of suppurative otitis media.
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  • A Comparative Double Blind Study with Cefaclor
    Shunkichi BABA, Haruji KINOSHITA, Yoshito MORI, Kenji SUZUKI, Shozo KA ...
    1985 Volume 31 Issue 5 Pages 1047-1065
    Published: September 20, 1985
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Sultamicillin (SBTPC) was compared with cefaclor (CCL) and evaluated as for the efficacy and safety in the treatment for 255 patients with acute lacunar tonsillitis in a double blind study. 375mg of SBTPC or 250mg of CCL were administered orally after a meal three times a day. The clinical efficacy rates of SBTPC and CCL were judged by attending doctors to be 91.9% (91/99), and 91.1% (82/90), respectively, and those judged by the committee were 80.8% (80/99), and 75.6% (68/90), respectively. There was no significant difference between SBTPC and CCL. In the patients with severe symptoms, SBTPC showed excellent efficacy in 11 out of 14 patients (78.6%), and CCL in 2 out of 8 patients (25.0%). In the judgment of attending doctors, SBTPC was significantly superior to CCL (P<0.05). The bacteriological effectiveness (eradication rate) was 98.9% (91/92) in SBTPC group and 97.7% (85/87) in CCL group. There was no statistically significant difference between two groups. The rate of side effect occurrence was 2.6% (3/114) in SBTPC group and 0.8% (1/112) in CCL group, with no significant difference between the two groups, no severe side effects were observed in either groups.
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