Abstract
The concentration of FOM in otorrhea was determined by paper disc assay in suppurative otitis media. The following results were obtained: FOM concentration in otorrhea, ranged from 90.63 to 162.5μg/ml (mean 125.63μg/ml) at 10 minutes, 68.75 to 100.0μg/ml (mean 83.75μg/ml) at 30 minutes, and 26.57 to 71.88 jig/ml (mean 50.94μg/ml) at 60 minutes after administration of 300μg/ml FOM solution in the tympanum. On the basis of these results, it is concluded that FOM is a useful antibiotic for the treatment of suppurative otitis media.
