Abstract
A case of Werner's syndrome with hoarseness was reported. The patient was a 35 year-old male whose parents were cousins. The patient had undergone an operation on his bilateral cataracta at the age of 21, but his left eye was eventually removed at age 28 due to glaucoma. He was short with gray hair, scleroderma-like skin and hoarse-voiced. He was diagnosed to have mild diabetes mellitus and hypergonadotrophic hypogonadism. His vocal cords were found to be yellow and atrophic, with deep sulci. His voice was very breathy on auditory impression. His maximam phonation time was 6 45, his usual spoken pitch was 300 Hz and speech range was d→a. Intracordal silicon injections followed by general administration of androgen and voice training resulted in a considerable improvement.
