Abstract
It is well known that there are three types of bronchial reactions in asthma: Immediate response (IR), late response (LR) and delayed response (DR). It is also reported that similar responses are seen in the skin. In this study, we examined the three types of skin reactions in 74 subjects with Japanese cedar pollinosis. Twenty cases (27.0%) had a LR, 26 cases (35.1%) had a DR for a skin test against Japanese cedar. In comparison, only 15 of 140 cases (10.7%) of house dust allergy showed a positive LR for the HD skin test and 5 (3.6%), a DR for the HD skin test. There was no correlation between late onset skin response and severity of nasal symptoms. Late onset skin tests tended to be positive for elder patients. Eosinophils and IgE levels tended to be lower in the LR positive cases. The levels of CHSO increased in several cases, but there was no correlation to skin responses. These findings seem to warrant an examination of the correlation between skin and nasal responses.
