Abstract
The introduction of antibiotics has reduced rhinogenic intracranial complications, but mortality rate is not low even at the present time because of blood-CSF barrier which degrades antibiotic efficacy. Four cases of intracranial complications caused by paranasal sinus infection were reported as follows: Case 1: A 12-year-old male with subdural abscess due to acute frontal sinusitis. Case 2: A 10-year-old female with brain and subdural abscess due to acute frontal sinusitis. Case 3: A 58-year-old male with orbital apex syndrome, meningitis and sepsis arising from a leaking sphenoid sinus pyocele. Case 4: A 20-year-old male with subdural abscess due to acute frontal sinusitis. Clinical diagnosis was supported by CT findings. All of these cases were successfully treated with chemotherapy and surgical drainage. Prompt diagnosis and early treatment is of crucial importance.
