A clinical study of Tosufloxacin in otorhinolaryngological infections

Abstract

A clinical study was conducted on the effect of Tosufloxacin, a new oral pyridone-carboxylic acid antibiotic agent, in 92 cases of otorhinolaryngological infections diseases. The conclusions of this study are summarized as noted below: 1) The overall efficacy rate was 79%, while the efficacy rate was 88% in acute infections, and 71% in chronic infections.
2) The efficacy rate of each infectious disease was as follows; Pharyngolaryngitis 100%, tonsillitis 95%, otitis media 63%, paranasal sinusitis 73%.
3) The efficacy rate of gram positive organism infections was 88%, while that for gram negative organism infections was 100%.
4) Mild diarrhea was observed as a side effect in only 1 case.
The above results therefore suggest that Tosufloxacin is a useful drug for the treatment of otorhinolaryngological infections.