Abstract
We pointed out several differences between two types of extraesophageal manifestations, namely cough and globus sensation, in gastroesophageal reflux disease by analyzing the data obtained from of pre-treatment questionnaires and symptom diaries. We carefully analyzed habitual factors. Patients who were treated in various ways for gastroesophageal reflux disease and thereafter recovered from their symptoms were enrolled as patients who had suffered from gastroesophageal reflux disease. In comparison to the patients in the laryngoesophageal group (n=13), whose chief complaints were globus sensations, the patients in cough group (n=29), whose chief complaints were cough symptoms, tended to have a significantly higher frequency of eating of “spicy foods”(p<0.05) and “sour foods”(p<0.05), while they also tended to have a shorter sleep time (p<0.05). By analyzing the smaller groups, who had answered a more detailed questionnaire, the patients in the laryngoesophageal group were thus found to have a significantly more frequent feeling of cold intolerance, and they also tended to walk significant less frequently on a daily basis. These results suggested that several environmental factors, such as eating habits and the lifestyle habits, clearly appeared to influence the development of these two different symptoms in some way.
