1966 Volume 69 Issue 4 Pages 867-875
The enzymatic ATP-hydrolyzing system in the stria vascularis and spiral ligament of the normal guinea pig was investigated. The existence of membrane ATPase, which is said to be closely related to the active transport of sodium and pot-assium across biological membranes, was establis-hed. The membrane ATPase in the present study was found to be similar in many respects to that found in various tissues.
The activity of the membrane ATPase in the stria vascularis and spiral ligament was considered to be fairly high in comparis-in to other secretory tissues. The distribution of the enzyme activity among various portions of the membranous labyri-nth was also demonstrated.