抄録
Hemophilia A is an X-linked hereditary disease. We describe herein a patient with multiple fractures of the facial bones, who was diagnosed with hemophilia A during treatment. A 15-year-old boy presented with multiple fractures of the facial bones at Hitachi, Ltd. Mito General Hospital. He underwent a repair operation for the fractures. Severe epistaxis recurred after the operation, and he was referred to Tsukuba University Hospital for further evaluation and treatment. On admission, laboratory testing revealed prolonged activated partial thromboplastin times (APTT) and decreased activity of factor VIII, which led to a diagnosis of hemophilia A. Administration of a coagulation factor VIII product prevented bleeding. The clinical phenotype is not always the same among hemophilia patients, thus, the possibility of previously undetected hemophilia has to be considered when treating unexpected severe bleeding.
