抄録
Boron Neutron Capture Therapy (BNCT) is the next generation radiotherapy approach to selectively destroy only cancer cells, which is based on the neutron capture reaction that occurs when nonradioactive boron (10B) is irradiated with neutrons of low (thermal) energy. It is possible to kill the cancer cells only, as a minimally invasive therapy, while causing less damage to the surrounding normal cells, through the selectively incorporation by cancer cells of boron compound, BPA and/or BSH, and then irradiating the cells with epithermal neutrons. BNCT is suitable for malignant brain tumors or recurrent radiation-resistant head and neck cancers. The cyclotron-based neutron source is a promising alternative to reactor-based neutron sources for treatments with BNCT.
