扁桃周囲膿瘍の重症化に関与する因子の検討

抄録

Background: Based on the background factors and results of blood tests in patients with peritonsillar abscess, we investigated the factors involved in the prolongation of hospitalization and progression to deep neck abscess of these patients.

Objective and Methods: We studied the data of 113 patients with peritonsillar abscesses (including those in whom the condition progressed to deep neck abscesses) who were hospitalized at our department during the 3-year period from August 2014 to July 2017. Data of patients who needed hospitalized treatment for 7 days or more, including the age, BMI, sickness period, white blood cell count, serum CRP, serum total protein, serum albumin, blood glucose, blood HbA1c, and eGFR at the first examination, and the neck factors in the cases that progressed to deep cervical abscess were examined using t-tests.

Results: The blood test items and background factors at the first visit were compared according to the length of hospitalization. The results revealed that prolonged hospitalization was associated with higher values of age, peripheral blood white blood cell count, serum CRP value and blood glucose, and lower values of the serum total protein, serum albumin, and eGFR.

Conclusions: Factors that were associated with a longer hospital stay in this study were relatively high values of age, peripheral blood white blood cell count, blood glucose and serum CRP, and relatively low values of the serum total protein, serum albumin, and eGFR. The disease duration, BMI and HbA1c were not identified as significant factors. Stepwise multiple regression analysis to identify factors associated with prolonged hospitalization identified the blood glucose and serum albumin levels measured at the first visit as significant predictors of a prolonged hospital stay and higher severity of the illness. Our findings suggested the importance of measuring these factors for predicting the progression to deep cervical abscess.