Abstract
The clinical effect of dihydroergotamine (DHE) was studied in 35 patients with orthostatic circulatory disorders and/or peripheral vertigo, principally Meniere's disease. These effects were assessed by subjective and objective parameters. Equilibrium and auditory functions were evaluated before and after medication by the same doctors. The drug dosage was 3-6mg of DHE daily for four weeks.
1) DHE was effective in 29 of 35 patients (82.8%) as judged by both subjective and objective parameters.
2) Subjective symptoms improved in 88.5% cases and objective symptoms in 82.8%.
3) No side-effects were observed during treatment.
Thus, DHE seemed to be effective and safe in the treatment of orthostatic circulatory disorders with or without peripheral vertigo.
