The clinical efficacy of KBT-1585, a new oral ampicillin ester, was investigated using a total of 20 patients with suppurative otitis: acute otitis media (2 cases) and chronic otitis media with exacerbation (18 cases). The results showed that KBT-1585 was highly effective against chronic otitis media with exacerbation with respect to clinical and bacteriological efficacy.
