Long-term Effects of Dilazep Dihydrochroride in Patients with Vertigo of Peripheral Vestibular Origin

Abstract

The long-term therapeutic effects of Dilazep dihydrochroride was investigated in patients with peripheral vestibular vertigo, mainly Meniere's disease and positional vertigo. A total of 45 patients were treated with Dilazep dihydrochroride (300mg/day) for 6 months. The therapeutic effectiveness was evaluated by analysing clinical symptoms and signs. There was subjective improvement in 85.2% of the patients and objective improvement in 74.1 %. The overall rate of improvement was 74.1 %. The frequency of vertigo significantly decreased after the treatment. There were no adverse reaction to this drug. These results indicate that Dilazep dihydrochroride is effective in the treatment of the peripheral vestibular vertigo.