ヒト上顎洞粘膜分泌細胞の定量的組織化学

抄録

Histochemical quantitation of mucopolysaccharides in the maxillary mucosa was performed on postmortem specimens. The posterior and medial walls of the maxillary sinuses were removed from 27 adults with normal sinuses and 57 adults with chronic sinusitis. Both goblet cells and submucosal gland cells were stained by Alcian blue at various pH levels and with periodic acid-Schiff with or without sialidase digestion.
There was no significant difference in the number of goblet cells between the normal and chronic sinusitis specimens. Submucosal gland cells were more dense in the sinusitis than in the normal tissues, especially in the posterior maxillary wall specimens. In the goblet cells, more than 75% of the mucopolysaccharide was neutral in the normal group, and more than 90% was sulphated in the sinusitis group. In the submucosal layers, 90% of the gland cells contained neutral mucopolysaccharides in the normal group, while sulphated and sialidase sensitive mucopolysaccharides were
present i n 75% of the cells in the sinusitis group.