Long-Term Results of Treatment for Carcinoma of the Maxillary Sinus

Abstract

Seventy-three patients with previously untreated carcinoma of the maxillary sinus, treated during an 11-year period were investigated retrospectively
The overall three-year and five year survival rates were 51.5% and 42.7% respectively. The five-year survival rate for the group treated with combined therapy consisting of local chemotherapy, radiation and necrotomy was 12.9%, it was 54.8% in the group treated with combined therapy followed by surgery, such as partial or total resection of the maxilla.
The most successful treatment was intraarterial infusion of adriamycin (bolus) and 5-FU (continuous), combined with radiotherapy and necrotomy, followed by surgery. The five-year survival rate in this group was 61.7%.