Abstract
The clinical effects of eperisone hydrochloride (Myonal®) alone or combined with other drugs (vitamin, tranquilizer) on tinnitus was evaluated in 77 patients (43 males and 34 females).
The clinical effects were excellent in 11 cases (14.3%), good in 12 cases (15.6%), fair in 10 cases (13.0%) and not effective in 43 cases (55.8%).
The effective rate was over 50% in tinnitus patients with central vertigo, sudden deafness and Meniere's disease. As to age, the agent was most effective in the 4th and 5th decades. Administration for over 8 weeks was more effective than less than 8 weeks. High pitch tinnitus responded better to the treatment than low pitch tinnitus. Side effects were noted in 11 cases (14.3%). There were neurological and gastrointestinal complaints.
