耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
頭頸部悪性リンパ腫に対するCDDP-PEP療法
越智 健太郎大西 純夫待木 健司西川 典秀友田 幸一大橋 徹
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1989 年 82 巻 6 号 p. 857-865

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Cis-platinum (CDDP) is well known as an effective and safe drug in the treatment of malignant tumors, especially squamous cell carcinoma. Although it is effective against malignant lymphoma, only a few reports have been published on its use in patients with malignant lymphoma.
We treated eight patients with non-Hodgkin's lymphoma of the head and neck region with a combination of CDDP and Peplomycin (PEP).
Six patients had complete remissions, and two patients had partial remissions. All side effects were mild and transient.
The combination of CDDP and PEP is effective against malignant lymphoma and should have merits incorporation into protocols of chemotherapy for malignant lymphoma, especially non-Hodgkin's lymphoma.
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