慢性副鼻腔炎における寒冷凝集素価の検討
―副鼻腔気管支症候群との比較検討―
1989 年 82 巻 8 号 p. 1081-1086
詳細
1989 年 82 巻 8 号 p. 1081-1086
We measured the level of cold hemagglutinin (CHA) in 129 cases of chronic paranasal sinusitis (CS) without bronchial involvement and 31 cases of sinobronchial syndrome (SBS). We also measured the level of CHA in 43 healthy subjects without any apparant hematologic, respiratory or liver disease as a control group.
The level of CHA in CS was significantly higher than that in the control group (p<0.05) and was significantly higher in SBS than in CS (p<0.05). A positive correlation was observed between the severity of chronic sinusitis and the elevation in the level of CHA.
These results suggest that CHA elevation is caused by chronic inflammation of the upper and lower respiratory tract, and that an autoimmunine mechanism plays a role in the pathogenesis of CS and SBS.
