Abstract
A 70-year-old man was admitted to the hospital because of a large left submandibular mass, 7×5×5cm. The tumor but it had been growing slowly for 50 years, enlarged suddenly, so we removed it together with adjacent lymph nodes. The pathohistological examination showed adenosquamous cell carcinoma accompanied by specific hyalinization. The hyalinization was considered to be related to the enlargement of the tumor and to the development of squamous cell carcinoma. Three years after the first operation, squamous cell carcinoma recurred. The adenosquamous cell carcinoma should be treated more vigorously at the initial stage.
