スギ花粉症に対するトリルダン®の予防効果

抄録

To study the prophylactive effect of Triludan® (Terfenadine) on Japanese cedar pollinosis, we administered Triludan® to patients before or after the start of the dispersion of pollen in the air in the Gifu and Takayama regions. The nasal symptoms of the two groups were compared.
Triludan® treatment started before dispersion significantly inhibited nasal discharge during the peak time and significantly prolonged the time taken to reach the peak for nasal discharge and sneezing.
The prophylactive effectiveness was fair or good in 53.2% of those treated. In a questionaire survey, 42.8% of the patients replied that they noted some prophylactive effect.
Nasal symptoms were milder in those treated before than in those treated after the start of pollen dispersion both in the Gifu region where the pollen count is high and in the Takayama region where it is low.