耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
鼻アレルギーに対するKetotifen点鼻薬の効果
井上 功山本 砧三武嶋 寛剛中小 路澄子貞岡 達也坂哲 郎垣鍔 典也坂倉 淳牧本 一男高橋 宏明和田 公平大森 研史林 伊吹藤田 隆夫渡辺 猛世藤澤 俊二宇野 功野中 隆三郎
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1994 年 87 巻 7 号 p. 985-995

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The effectiveness, safety and usefulness of ketotifen nasal spray were investigated in 163 patients with allergic rhinitis. Ketotifen nasal spray (0.05mg/puff) was given four times daily for 4 weeks or more. “Slight to high” improvement was recorded in 92.4% of patients and “moderate to high” improvement in 61.0%.
Overall usefulness was very high for both perennial and seasonal allergic rhinitis. Side effects were noted in six patients (3.7%). Drowsiness was noted in five patients and nasal mucosal pain in only one.
The results of this study suggest that ketotifen nasal spray is very useful in the treatment of allergic rhinitis.

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