The effectiveness, safety and usefulness of ketotifen nasal spray were investigated in 163 patients with allergic rhinitis. Ketotifen nasal spray (0.05mg/puff) was given four times daily for 4 weeks or more. “Slight to high” improvement was recorded in 92.4% of patients and “moderate to high” improvement in 61.0%.
Overall usefulness was very high for both perennial and seasonal allergic rhinitis. Side effects were noted in six patients (3.7%). Drowsiness was noted in five patients and nasal mucosal pain in only one.
The results of this study suggest that ketotifen nasal spray is very useful in the treatment of allergic rhinitis.