A patient who developed toxic shock syndrome (TSS) following sinus surgery is described. A 22-year-old male complaining of pyrexia (39°C), general fatigue, watery diarrhea, nausea, muscle soreness and sore throat was admitted as an emargency patient to one of our infirmaries 19 days after sinus surgery had been performed at another hospital. Hypotension with a systolic blood pressure of 80 mmHg and erythroderma on his palm and sole were noted. Methicillin-resistant Staphylococcus aureus (MRSA) was detected in pus secreted from the right nasal cavity. Appropriate hydration, antibiotics and local clearance of the infection was applied in the management of the TSS. Good prognosis ensued without γ-globulin therapy. TSS should currently be con-sidered as an important complication of nasal surgery.