抄録
The rapeutic approaches in the treatment of sudden deafness patients unresponsive to steroid treatment remains controversial. Defibrinogenation therapy using batroxobin is thought to be useful, because vascular disorders are potentially involved in the etiology of sudden deafness. Batroxobin was administered to twelve patients showing little improvement after steroid treatment. The patients included three males and nine females, average age 48.0 years, with a mean heahng level of 85.0dB.
Following defibrinogenation therapy, eight of the twelve patients showed good recovery of hearing without any side effects. In this report, we summarize the results of defibrinogenation therapy and discuss the importance of these results.