We report a case of paranasal aspergillosis and brain abscess of the sphenoid sinus. The patient was a 47-year-old male with poorly controlled diabetes mellitus who complained of unilateral visual loss. He was admitted to our hospital and CT showed an isolated mass lesion in the sphenoid sinus. Therfore, he consulted our department. He was treated with endoscopic sinus surgery, and diagnostic tools histology and fungal culture, for Aspergillus confirmed the diagnosis. One week later, an MRI demonstrated that the invasive sphenoid aspergillosis invaded the skull base. The lingenhanced mass occupied the brain, and he lost unilateral eyesight.
