耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
非ホジキンリンパ腫
―咽頭, 頸部リンパ節原発症例の検討―
馬越 智浩高橋 廣臣八尾 和雄稲木 勝英中山 明仁永井 浩巳岡本 牧人
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2001 年 94 巻 1 号 p. 65-69

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Between June 1988 and December 1996, 57 patients with non-Hodgkin's lymphomas of the head and neck were treated at our department. The primary lesion was located in Waldeyer's ring in 31 patients and cervical lymph nodes in 26 patients. These patients, who were diagnosed as Stage I or II, were treated with chemotherapy and radiation. The chemotherapy regimen consisted of pirarubicin (45mg/m2; day 1), cyclophosphamide (750mg/m2; dayl), vindesine (1.5mg/m2; day 1) and predonisolone (100mg/body; days 1-5). The complete and partial response rates were 79% and 82% respectively. The five-year estimated overall survival rate calculated by Kaplan-Meier method was 75%. We concluded that the combination of chemotherapy regimen (THP-CVP) and radiation were useful and safe for treating non-Hodgkin's lymphomas of the head and neck.

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