A 57-year-old male was admitted with severe fatigue and systemic lymphadenopathy. Surgical biopsy specimens revealed Castleman's disease of hyaline vascular type. After admission, Guillain-Bane syndrome developed and the ptient was treated with predonisolone and plasma pheresis was given. The patient's symptoms and lymphadenopathy responded and disappeared rapidly. Five months later, systemic lymphadenopathy recurred. Surgical biopsy was performed and the histological features were consistent with a diagnosis of peripheral T-cell lymphoma of diffuse mixed type, probably resulting from the progression of the Castleman's disease.
