A case of severe oropharyngeal cancer pain controlled with intravenous high dose morphine is reported.
The patient was treated with enteral morphine at first, but as the tumor increased in size, pain between the administration of morphine occurred. With the continuous intravenous high dose morphine up to 3, 360 mg/day, good pain relief was achieved. Seizure occurred during the continuous intravenous morphine administration, but no other severe side effects occurred.