抄録
Wegener's granulomatosis is necrotic granulomatosis angitis frequently starting with otolaryngological symptoms. We treated two patients with a history of otitis media with hearing loss. The laboratory results for both patients were positive for C-ANCA; one patients had typical pathologic appearance in the nasal mucous membrane, but the other had no typical pathologic signs. The patients were diagnosed with Wegener's granulomatosis based on the clinical, histological and laboratory findings, and predonisolone and azathioprine were administered.
The diagnosis and treatment of Wegener's granulomatosis with ear symptoms is also discussed.
