Practica Oto-Rhino-Laryngologica
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
Clinical Efficacy of Choto-san with Merislon and Serenal® on Tinnitus
Keiko NISHIOKAHisako MATSUOKAShigeko NISHIOKAMami YAMAMOTONaoto ICHIHARAYumiko ICHIHARA
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2002 Volume 95 Issue 4 Pages 413-420

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Abstract
Forty-two patients complaining of tinnitus were treated orally with Choto-san (a Chinese medicine), Betahistine Mesilate, and Oxazolam for one month. Overall effectiveness ratings: Twenty-four (57.1%) patients seemed to improve in tone volume, twenty-two (52.4%) in durability, and sixteen (38.1%) in worrying. Even in the early stage of this experiment, twenty-six percent of the subjects seemed to have a greater improvement in tinnitus than those treated with only one of the medicines. It is suggested that these medicines are promising in the treatment of tinnitus because there is a synergic effectiveness in their combination.
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