耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
血清GM-CSF高値を認めた甲状腺未分化癌例
黒瀬 誠佐藤 純坪田 大石川 忠孝小西 正訓氷見 徹夫
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2002 年 95 巻 8 号 p. 837-841

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We report here a case of anaplastic thyroid carcinoma with a high serum GM-CSF level. A 75-year-old man was admitted because of a rapidly enlarging neck mass. Investigation demonstrated that the neck mass consisted of anaplastic carcinoma of the throid gland. Although radiation therapy was performed, he died 3 months after admission due to respiratory insufficiency caused by metastatic lung carcinoma. Marked elevation of the number of leukocytes to 95, 700/mm3 was observed during the clinical course, and an increase in the GM-CSF level (46.90pg/dl) was demonstrated in the serum. We discuss the clinical course and prognosis of this tumor based on our case with reference to the literature.
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