We report a case of acute myocardial infarction presenting as atypical throat pain. A 76-year-old man complaining of throat pain was admitted to the otorhinolaryngology division of Osaka Police Hospital. Physical examination and laryngoscopy did not detect any abnormality. Then we considered the possibility of referred pain due to coronary heart disease, and ordered electrocardiogram and serum troponin T, which showed acute coronary syndrome. Finally the patient was diagnosed as anterior acute myocardial infarction and underwent emergent treatment in the Cardiovascular Division. Unexplained throat pain can be referred pain due to ischemic heart disease.