耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
von Willebrand 病患者の口蓋扁桃摘出例
河口 幸江荒木 進井上 斉萩原 晃高木 秀朗竹之内 剛鈴木 衞
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2006 年 99 巻 8 号 p. 657-660

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von Willebrand's disease (vWD) is a frequent hereditary bleeding disorder due to a quantitative and/or qualitative deficiency of von Willebrand's factor (vWF). When surgery is considered coagulant therapies must be planned. There are several coagulant therapies. Factor VIII concentrates that contain von Willebrand's factor are most commonly used.
We report a patient with von Willebrand's disease who underwent tonsillectomy. The patient was a 29 year old man diagnosed as having von Willebrand's disease at 7 year old. He had previously demonstrated massive hemorrhage of the liver following a fine needle biopsy. We selected the therapy using the factor VIII concentrates containing von Willebrand's factor. Factor VIII concentrates containing von Willebrand's factor were administered preoperatively and postoperatively for 6 days. Bleeding was successfully controlled during and after tonsillectomy.

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