von Willebrand's disease (vWD) is a frequent hereditary bleeding disorder due to a quantitative and/or qualitative deficiency of von Willebrand's factor (vWF). When surgery is considered coagulant therapies must be planned. There are several coagulant therapies. Factor VIII concentrates that contain von Willebrand's factor are most commonly used.
We report a patient with von Willebrand's disease who underwent tonsillectomy. The patient was a 29 year old man diagnosed as having von Willebrand's disease at 7 year old. He had previously demonstrated massive hemorrhage of the liver following a fine needle biopsy. We selected the therapy using the factor VIII concentrates containing von Willebrand's factor. Factor VIII concentrates containing von Willebrand's factor were administered preoperatively and postoperatively for 6 days. Bleeding was successfully controlled during and after tonsillectomy.