Pleomorphic adenoma is recognized as a common neoplasm of the salivary gland. More than 90% of pleomorphic adenomas originate from the parotid gland. On the other hand, the minor salivary gland of the hard palate as the origin shows a relatively low frequency. We report on the different clinical features of 2 cases of pleomorphic adenoma arising from the hard palate. The first case was a 65-year-old female. Although a fine needle aspiration biopsy (FNAB) showed suspected class V adenoid cystic carcinoma, there were no clinical findings on the diagnostic images or symptoms suggesting malignancy. The second case was a 34-year-old female whose FNAB showed a suspected class III pleomorphic adenoma, which was consistent with the final pathological diagnosis from the resected specimen. These findings suggest that FNAB is not a definitive finding, but one of the diagnostic tools to obtain full information.
