抄録
Sinusitis is commonly found, but lesions localized in the sphenoid sinus are rarely associated with sinusitis. We report herein on 21 cases of isolated sphenoid sinus disease (ISSD) treated surgically at the Department of Otolaryngology, Yamaguchi University, Graduate School of Medicine between March 2008 and March 2012. Diagnosis was made on the basis of history, clinical signs, nasal endoscopy, and imaging techniques with CT/MRI. The final diagnosis of ISSD was established after histopathological examinations of the excised surgical specimen. The pathologies included fungal diseases (48%), sphenoid sinusitis (28%), sphenoid cysts (19%), and tumorous tissue (5%). The initial symptom was headache (62%), followed by rhinorrhea (19%). An endoscopic sphenoidectomy was performed through the nasal septum in 15 patients and was useful for total removal of the lesion.