1986 Volume 1986 Issue Supplement4 Pages 189-195
Adult laryngeal papilloma, especially keratinized papilloma tends to exhibit malignant transformation. Two patients with papilloma who developed carcinoma later are reported. The first case was a 50-year-old male who underwent laryngoscopic removal in 1981. He returned three years later with multiple tumors of verrucous carcinoma of the larynx, and underwent total laryngectomy. The second case was a 58-year-old male, who had underwent repeated laryngoscopic removal and laser surgery since 1981. Two years later, the tumor recurred and biopsy specimen revealed squamous cell carcinoma. Retrospective histopathological study of the two cases showed that the malignant lesion was present in a part of the initial tissue specimen.
