Practica oto-rhino-laryngologica. Suppl.
Online ISSN : 2185-1557
Print ISSN : 0912-1870
ISSN-L : 0912-1870
Caloric Response in Patients Treated with Streptomycin
Shigeaki ShirabeTetsuya Tsuda
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1986 Volume 1986 Issue Supplement8 Pages 173-178

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Abstract

On 27 patients treated with streptomycin sulfate, we examined whether or not vestibular reaction and especially caloric nystagmus response would be significant for the detection of their disequilibrium. These patients were 22 males and 5 females averaging 51 years old, and average dose was 20 gr. In individual cases, repeated caloric test not necessarily made it easy to detect early disequilibrium.
Using a method of irrigation at 30 degrees and 40 se c. according to Hallpike's method, caloric response was compared between 32 patients (averaging 50 years old)with dizziness of unknown origin who were judged to have normal vestibular peripheral function and 20 streptomycin group. Strepomycin group showed reduction in duration, frequency and maximum eye speed of slow phase, of 10%,25% and 40%.
Two cases of bilateral vestibular hypofunction with Jumbling phenomenon w ere reported. A case with some right-left difference in vestibular function was intractable. And another case with recovered subjective symptoms showed a slight recovery of bilateral caloric response, as well.

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