Immunohistochemical Analysis of the Lateral Wall of the Endolymphatic Sac of Meniere's Patients and a Control

Abstract

The lateral wall of the endolymphatic sac of nine patients of Meniere and one of acoustic tumor as control was undergone in a immunohistochemical procedure using FITC labeled antihuman IgA, IgG, IgM, IgE, C₁q, C₃, C₄, and Fibrinogen into the freesed specimen and the luminescent-microscopy.
The highest rate of p o sitive luminescense was yielded in IgG (83%) comparing other immunoglobulin, i. e. IgA (63%), IgM (38%). In a control, there was none.
This result might be understood as an expression of an immunological disorder in the endolymphatic space including the sac itself.