Electrophysiological Study in Congenital Hypothyroidism (Cretinism)

Abstract

Auditory brain-stem response (ABR) and electrocochlcography (ECoG) were recorded on II children with congenital hypothyroidism. The mean N₁latency increased and its latency-intensity (L-I) curve became steeper at a low intensity (P<0.01). The mean N₁-V interval tended to decrease and its L-I curve tended to become steeper at a low intensity. These findings suggest that the cochlear abnormality causes hearing impairment in congenital hypothyroidism.