A patient with Findings of Mikulicz's Disease and Sjögren's Syndrome

Abstract

We reported a patient with findings of Mikulicz's disease and Sjögren's syndrome. A 44-year-old woman who complained of xerostomia and bilateral enlargement of the lacrimal and submandibular glands was referred to our clinic in January,1988. Physical examination, X-ray examination, computed tomography and scintigram revealed remarkable swelling of the lacrimal and submandibular glands and the decreased salivation. Serological examination suggested immunological abnormalities. Histological examination of the right submandibular gland showed marked fibrosis, lymphocytic infiltration and destruction of acini; these findings were compatible with chronic sclerosing sialoadenitis. In March,1989, bilateral swelling of the parotid glands appeared. However, the sialogram of the parotid gland showed normal appearance.