A Case of Triple Cancer, Including Adenocarcinoma of the Nasal Cavity

Abstract

A case of triple cancer, including adenocarcinoma of the nasal cavity is reported. The patient was a 75-year-old man complaining of nasal obstruction and was diagnosed with adenocarcinoma of the left nasal cavity. A general examination later revealed that he also had gastric cancer. Both lesions were surgically treated (extirpation of the tumor of the left nasal cavity and subtotal gastrectomy). Histopathological analyses of the surgical specimens revealed early stage well differentiated tubular adenocarcinoma in the gastric lesion as well as the nasal cavity tumor. We considered, however, that each cancer was distinct, because early gastric cancer rarely metastasizes to other organs and there was no evidence of metastasis to the lung, liver, lymph node and so on. About a year later, he was diagnosed with laryngeal carcinoma (squamous cell carcinoma, T1 aN0M0). He was treated with radiotherapy. The patient is disease free at present.
Primary adenocarcinoma of the nasal cavity is rare. Triple cancer, including adenocarcinoma of the nasal cavity, has not previously been reported in Japan.