リンパ腫細胞の浸潤を認めたワルチン腫瘍の1例

抄録

Warthin's tumor and malignant tumors rarely occur simultaneously. We report here a case of Warthin's tumor combined with a malignant lymphoma. The patient, a 74-year-old man, visited our clinic and reported a mass under his left parotid gland. An imaging study suggested that the mass was a Warthin's tumor of the parotid gland, and a superficial parotidectomy was performed. A diagnosis of Warthin's tumor was made on the basis of the histopathological findings, which also showed partial destruction of the capsule by lymphocyte infiltration. The cervical lymph nodes became enlarged by the 3rd week after surgery, and the axillary and lng-uinal lymph nodes enlarged by the 5th week after surgery. Histopathological and immunohistological studies demonstrated that the enlarged lymph nodes were due to a T cell type non-Hodgkin's malignant lymphoma. Lymphoma cell infiltration in the resected Warthin's tumor was also confirmed. Chemotherapy proved ineffective, and the patient died from the tumor. Warthin's tumor is usually benign; however, caution should be observed when the tumor shows a tendency to enlarge rapidly, as this may be indicative of malignant transformation of the Warthin's tumor or a combined malignant tumor.