抄録
Review of the respiratory effects of experimental, occupational, and community exposure to nitrogen dioxide (NO2) and ozone (O3) is presented. NO2 and O3 can penetrate the respiratory upper airway more readily than can SO2, and this difference in the penetration rate may be one of the causes for that the pulmonary damages with relatively high concentrations of NO2 and O3, deep irritant, are different from those with SO2. More detailed researches are required for evaluation of lower concentration effect of these gases, but it is emphasized that in addition to its own deleterious effect on the lung, NO2 is a causative agent of photochemical oxidants.