Abstract
The anti-obesity action of lactic acid bacteria was evaluated using in vitro and in vivo assay systems. From 293 strains of lactic acid bacteria, several Lactobacillus strains showed strong inhibitory activity against pancreatic lipase. The effects of seven Lactobacillus strains on plasma triacylglycerol elevation in rats with oral lipid loading were examined. Rats administered the lipid emulsion containing Lactobacillus gasseri NLB367 showed lower plasma triacylglycerol levels than those fed the lipid emulsion only.
Lactobacillus gasseri NLB367 inhibited the hydrolysis of triacylglycerol by pancreatic lipase in vitro and elevation of the plasma triacylglycerol level after oral administration of the lipid emulsion in the rats. These results suggest that L.gasseri NLB367 might improve lipid metabolism as a probiotic.
